Vaccination is one of the most impactful things you can do for your cat’s long-term health. Yet many owners are uncertain about which vaccines are required, which are optional, and how the schedule works across a cat’s lifetime. This guide answers all of it.
Core vs. non-core vaccines
The American Association of Feline Practitioners (AAFP) divides cat vaccines into two categories:
- Core vaccines — recommended for every cat regardless of lifestyle: FVRCP (feline viral rhinotracheitis, calicivirus, panleukopenia) and Rabies.
- Non-core vaccines — recommended based on risk factors: FeLV (feline leukemia virus), Bordetella, Chlamydophila felis, FIV.
Kitten vaccination schedule
| Age | Vaccines |
|---|---|
| 6–8 weeks | FVRCP (first dose) |
| 10–12 weeks | FVRCP (second dose), FeLV (if at risk) |
| 14–16 weeks | FVRCP (third dose), Rabies, FeLV second dose |
| 12–16 months | FVRCP booster, Rabies booster |
Adult cat schedule
After the initial series, most core vaccines move to a 3-year cycle. Rabies frequency depends on local law — many jurisdictions require annual rabies vaccination regardless of the vaccine label. Always confirm with your local vet.
Indoor-only cats: do they need vaccines?
Yes — with some exceptions. Rabies is legally required in most countries. FVRCP protects against airborne viruses that can enter your home on shoes or clothing. FeLV can be skipped for truly isolated indoor cats, but the risk is rarely zero. Discuss your cat’s specific situation with your vet.
What to expect after vaccination
Mild lethargy and soreness at the injection site are normal for 24–48 hours. Serious reactions (facial swelling, difficulty breathing, collapse) are rare but require immediate emergency care. Monitor your cat for 1 hour post-vaccine and have an emergency vet number ready.
Cost overview (US estimates)
- FVRCP: $25–$45 per dose
- Rabies: $15–$35
- FeLV: $25–$45
- Full kitten series (all visits): $150–$300 depending on location
Many humane societies and low-cost clinics offer significantly discounted vaccines for budget-conscious owners.
Questions about your cat’s specific vaccine needs? Drop them in the comments below.